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TitleFucosylated ubiquitin and orthogonally glycosylated mutant A28C: conceptually new ligands for Burkholderia ambifaria lectin (BambL).
Journal, issue, pagesChem Sci, Vol. 11, Page 12662-12670, Year 2020
Publish dateJun 17, 2020 (structure data deposition date)
AuthorsKuhaudomlarp, S. / Cerofolini, L. / Santarsia, S. / Gillon, E. / Fallarini, S. / Lombardi, G. / Denis, M. / Giuntini, S. / Valori, C. / Fragai, M. ...Kuhaudomlarp, S. / Cerofolini, L. / Santarsia, S. / Gillon, E. / Fallarini, S. / Lombardi, G. / Denis, M. / Giuntini, S. / Valori, C. / Fragai, M. / Imberty, A. / Dondoni, A. / Nativi, C.
External linksChem Sci / PubMed:34094460
MethodsX-ray diffraction
Resolution1.65 Å
Structure data

PDB-6zfc:
Fucose-binding lectin from Burkholderia ambifaria (BamBL) in complex with a fucosyl derivative
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

Chemicals

ChemComp-QJB:
2-[(2~{S},3~{S},4~{R},4~{a}~{S},10~{a}~{S})-2-methyl-3,4-bis(oxidanyl)-3,4,4~{a},10~{a}-tetrahydro-2~{H}-pyrano[2,3-b][1,4]benzoxathiin-7-yl]-~{N}-(3-oxidanylpropyl)ethanamide

ChemComp-HOH:
WATER

Source
  • burkholderia ambifaria (strain atcc baa-244 / ammd) (bacteria)
KeywordsSUGAR BINDING PROTEIN / fucose-binding lectin / glycomimetics

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