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TitleSYK Kinase domain in complex with azabenzimidazole inhibitor 2b
Journal, issue, pagesTo Be Published
Publish dateJun 9, 2020 (structure data deposition date)
AuthorsRead, J.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.73 - 1.97 Å
Structure data

PDB-6zc0:
SYK Kinase domain in complex with azabenzimidazole inhibitor 2b
Method: X-RAY DIFFRACTION / Resolution: 1.97 Å

PDB-6zcu:
syk in complex with 57262_SYKB-AZ13344324-2
Method: X-RAY DIFFRACTION / Resolution: 1.73 Å

Chemicals

ChemComp-QDZ:
~{N},~{N}-dimethyl-1-[1-[2-(1-methylindol-4-yl)-3~{H}-imidazo[4,5-b]pyridin-7-yl]pyrazol-4-yl]methanamine

ChemComp-HOH:
WATER

ChemComp-5JG:
6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-N-(piperidin-4-ylmethyl)-3H-imidazo[4,5-b]pyridin-7-amine

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / SYK Kinase TRANSFERASE INHIBITOR

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