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-Structure paper
Title | Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway. |
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Journal, issue, pages | Acs Chem. Biol., Vol. 15, Page 2529-2538, Year 2020 |
Publish date | Apr 16, 2020 (structure data deposition date) |
![]() | Xiao, X. / Elsayed, S.S. / Wu, C. / van der Heul, H.U. / Metsa-Ketela, M. / Du, C. / Prota, A.E. / Chen, C.C. / Liu, W. / Guo, R.T. ...Xiao, X. / Elsayed, S.S. / Wu, C. / van der Heul, H.U. / Metsa-Ketela, M. / Du, C. / Prota, A.E. / Chen, C.C. / Liu, W. / Guo, R.T. / Abrahams, J.P. / van Wezel, G.P. |
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Methods | X-ray diffraction |
Resolution | 1.08 - 2.08 Å |
Structure data | ![]() PDB-6ypz: ![]() PDB-6yq0: ![]() PDB-6yq3: ![]() PDB-6yq6: |
Chemicals | ![]() ChemComp-NDP: ![]() ChemComp-EDO: ![]() ChemComp-PEG: ![]() ChemComp-HOH: ![]() ChemComp-NAP: ![]() ChemComp-P7K: ![]() ChemComp-P7Q: ![]() ChemComp-SO4: |
Source |
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![]() | ANTIBIOTIC / lugdunomycin / keto-reduction / short chain alcohol reductase / Rossmann fold |