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TitleCo-crystallization and nanoESI-MS reveal dimer disturbing inhibitors and conformational changes at dimer contacts
Journal, issue, pagesTo Be Published
Publish dateMar 27, 2020 (structure data deposition date)
AuthorsNguyen, A. / Heine, A. / Klebe, G.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-6ygr:
tRNA-guanine Transglycosylase (TGT) in co-crystallized complex with 6-Amino-4-(2-phenylethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-NE8:
6-AMINO-4-(2-PHENYLETHYL)-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE

ChemComp-HOH:
WATER

Source
  • zymomonas mobilis subsp. mobilis zm4 = atcc 31821 (bacteria)
KeywordsTRANSFERASE / TGT / TRNA-GUANINE TRANSGLYCOSYLASE / GUANINE INSERTION ENZYME / HOMODIMER

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