+Search query
-Structure paper
Title | Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein-protein interactions. |
---|---|
Journal, issue, pages | Nat Commun, Vol. 11, Page 3954-3954, Year 2020 |
Publish date | Mar 27, 2020 (structure data deposition date) |
Authors | Sijbesma, E. / Visser, E. / Plitzko, K. / Thiel, P. / Milroy, L.G. / Kaiser, M. / Brunsveld, L. / Ottmann, C. |
External links | Nat Commun / PubMed:32770072 |
Methods | X-ray diffraction |
Resolution | 2.07 Å |
Structure data | PDB-6ygj: |
Chemicals | ChemComp-OQE: ChemComp-HOH: |
Source |
|
Keywords | STRUCTURAL PROTEIN / 14-3-3 / Stabilizer / protein-protein interaction / ChREBP / small molecule |