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-Structure paper
Title | Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target. |
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Journal, issue, pages | J. Biol. Chem., Vol. 295, Page 11656-11668, Year 2020 |
Publish date | Mar 16, 2020 (structure data deposition date) |
![]() | Skerlova, J. / Unterlass, J. / Gottmann, M. / Marttila, P. / Homan, E. / Helleday, T. / Jemth, A.S. / Stenmark, P. |
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Methods | X-ray diffraction |
Resolution | 2.36 - 2.406 Å |
Structure data | ![]() PDB-6yb8: ![]() PDB-6yb9: |
Chemicals | ![]() ChemComp-C2R: ![]() ChemComp-OK8: ![]() ChemComp-IMD: ![]() ChemComp-EDO: ![]() ChemComp-HOH: ![]() ChemComp-ANP: ![]() ChemComp-MG: |
Source |
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![]() | BIOSYNTHETIC PROTEIN / de novo purine biosynthesis / nucleotide metabolism / cancer target |