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TitleCrossing the Border: From Keto- to Imine Reduction in Short-Chain Dehydrogenases/Reductases.
Journal, issue, pagesChembiochem, Vol. 21, Page 2615-2619, Year 2020
Publish dateFeb 20, 2020 (structure data deposition date)
AuthorsRoth, S. / Stockinger, P. / Steff, J. / Steimle, S. / Sautner, V. / Tittmann, K. / Pleiss, J. / Muller, M.
External linksChembiochem / PubMed:32315494
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-6y4d:
Crystal structure of a short-chain dehydrogenase/reductase (SDR) from Zephyranthes treatiae in complex with NADP+
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • zephyranthes treatiae (plant)
KeywordsOXIDOREDUCTASE / asymmetric reduction / biocatalysis / imine reduction / mutagenesis / rational design / short-chain dehydrogenase/reductase / Zephyranthes treatiae / complex

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