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TitleMouse thymidylate synthase cocrystallized with dUMP and soaked in sulfamethoxazole
Journal, issue, pagesTo Be Published
Publish dateFeb 6, 2020 (structure data deposition date)
AuthorsMaj, P. / Jarmula, A. / Wilk, P. / Weiss, M.S. / Rode, W.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.297 Å
Structure data

PDB-6y08:
Mouse thymidylate synthase cocrystallized with dUMP and soaked in sulfamethoxazole
Method: X-RAY DIFFRACTION / Resolution: 2.297 Å

Chemicals

ChemComp-UMP:
2'-DEOXYURIDINE 5'-MONOPHOSPHATE

ChemComp-08D:
Sulfamethoxazole / antibiotic*YM

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsTRANSFERASE / Fragment Screening / Fragment / Inhibitor / Thymidylate Synthase

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