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-Structure paper
Title | Identification of potent inhibitors of the sortilin-progranulin interaction. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 30, Page 127403-127403, Year 2020 |
Publish date | May 21, 2020 (structure data deposition date) |
![]() | Stachel, S.J. / Ginnetti, A.T. / Johnson, S.A. / Cramer, P. / Wang, Y. / Bukhtiyarova, M. / Krosky, D. / Stump, C. / Hurzy, D.M. / Schlegel, K.A. ...Stachel, S.J. / Ginnetti, A.T. / Johnson, S.A. / Cramer, P. / Wang, Y. / Bukhtiyarova, M. / Krosky, D. / Stump, C. / Hurzy, D.M. / Schlegel, K.A. / Cooke, A.J. / Allen, S. / O'Donnell, G. / Ziebell, M. / Parthasarathy, G. / Getty, K.L. / Ho, T. / Ou, Y. / Jovanovska, A. / Carroll, S.S. / Pausch, M. / Lumb, K. / Mosser, S.D. / Voleti, B. / Klein, D.J. / Soisson, S.M. / Zerbinatti, C. / Coleman, P.J. |
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Methods | X-ray diffraction |
Resolution | 2.7 - 2.9 Å |
Structure data | ![]() PDB-6x3l: ![]() PDB-6x48: ![]() PDB-6x4h: |
Chemicals | ![]() ChemComp-UMJ: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-UP4: ![]()
ChemComp-UNL: ![]() ChemComp-UOY: |
Source |
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![]() | UNKNOWN FUNCTION / Protein Protein Interaction |