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-Structure paper
Title | Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies. |
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Journal, issue, pages | J. Med. Chem., Vol. 63, Page 4867-4879, Year 2020 |
Publish date | Jan 30, 2020 (structure data deposition date) |
![]() | Ghosh, A.K. / Kovela, S. / Osswald, H.L. / Amano, M. / Aoki, M. / Agniswamy, J. / Wang, Y.F. / Weber, I.T. / Mitsuya, H. |
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Methods | X-ray diffraction |
Resolution | 1.25 - 1.3 Å |
Structure data | ![]() PDB-6vod: ![]() PDB-6voe: |
Chemicals | ![]() ChemComp-NA: ![]() ChemComp-CL: ![]() ChemComp-GOL: ![]() ChemComp-T1R: ![]() ChemComp-FMT: ![]() ChemComp-HOH: ![]() ChemComp-ACT: ![]() ChemComp-T2R: |
Source |
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![]() | ANTIVIRAL PROTEIN / inhibitors / antiviral / multidrug-resistant / Chf-THF / backbone binding |