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TitleEvaluation of Bacterial RNA Polymerase Inhibitors in a Staphylococcus aureus -Based Wound Infection Model in SKH1 Mice.
Journal, issue, pagesAcs Infect Dis., Vol. 6, Page 2573-2581, Year 2020
Publish dateJan 17, 2020 (structure data deposition date)
AuthorsHaupenthal, J. / Kautz, Y. / Elgaher, W.A.M. / Patzold, L. / Rohrig, T. / Laschke, M.W. / Tschernig, T. / Hirsch, A.K.H. / Molodtsov, V. / Murakami, K.S. ...Haupenthal, J. / Kautz, Y. / Elgaher, W.A.M. / Patzold, L. / Rohrig, T. / Laschke, M.W. / Tschernig, T. / Hirsch, A.K.H. / Molodtsov, V. / Murakami, K.S. / Hartmann, R.W. / Bischoff, M.
External linksAcs Infect Dis. / PubMed:32886885
MethodsX-ray diffraction
Resolution4.02 Å
Structure data

PDB-6vjs:
Escherichia coli RNA polymerase and ureidothiophene-2-carboxylic acid complex
Method: X-RAY DIFFRACTION / Resolution: 4.02 Å

Chemicals

ChemComp-QZY:
3-{[benzyl(ethyl)carbamoyl]amino}-5-(4-phenoxyphenyl)thiophene-2-carboxylic acid

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

Source
  • escherichia coli (E. coli)
KeywordsTRANSCRIPTION / RNA polymerase Transcription

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