+Search query
-Structure paper
Title | Design, Synthesis, and Mechanism of Fluorine-substituted Cyclohexene Analogues of GAMA-Aminobutyric Acid (GABA) as Selective Ornithine Aminotransferase Inactivators |
---|---|
Journal, issue, pages | To Be Published |
Publish date | Dec 10, 2019 (structure data deposition date) |
![]() | Zhu, W. / Doubleday, P.T. / Catlin, D.S. / Weerawarna, P. / Butrin, A. / Shen, S. / Kelleher, N.L. / Liu, D. / Silverman, R.B. |
![]() | Search PubMed |
Methods | X-ray diffraction |
Resolution | 1.9 - 2.25 Å |
Structure data | ![]() PDB-6v8c: ![]() PDB-6v8d: |
Chemicals | ![]() ChemComp-PLP: ![]() ChemComp-QRM: ![]() ChemComp-HOH: ![]() ChemComp-O78: |
Source |
|
![]() | TRANSFERASE / Human Ornithine Aminotransferase (hOAT) / Mechanism Based Inactivator / PLP Hepatocellular Carcinoma (HCC) |