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-Structure paper
Title | Development of a covalent inhibitor of gut bacterial bile salt hydrolases. |
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Journal, issue, pages | Nat. Chem. Biol., Vol. 16, Page 318-326, Year 2020 |
Publish date | Sep 25, 2019 (structure data deposition date) |
Authors | Adhikari, A.A. / Seegar, T.C.M. / Ficarro, S.B. / McCurry, M.D. / Ramachandran, D. / Yao, L. / Chaudhari, S.N. / Ndousse-Fetter, S. / Banks, A.S. / Marto, J.A. ...Adhikari, A.A. / Seegar, T.C.M. / Ficarro, S.B. / McCurry, M.D. / Ramachandran, D. / Yao, L. / Chaudhari, S.N. / Ndousse-Fetter, S. / Banks, A.S. / Marto, J.A. / Blacklow, S.C. / Devlin, A.S. |
External links | Nat. Chem. Biol. / PubMed:32042200 |
Methods | X-ray diffraction |
Resolution | 2.71 - 3.51 Å |
Structure data | PDB-6ufy: PDB-6uh4: |
Chemicals | ChemComp-HOH: ChemComp-QC7: |
Source |
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Keywords | HYDROLASE / Bile Salt Hydrolase / Hydrolase/Hydrolase inhibitor / Bile Salt Hydrolase B. theta / Hydrolase-Hydrolase inhibitor complex |