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-Structure paper
Title | A requirement for an active proton delivery network supports a compound I-mediated C-C bond cleavage in CYP51 catalysis. |
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Journal, issue, pages | J. Biol. Chem., Vol. 295, Page 9998-10007, Year 2020 |
Publish date | Sep 23, 2019 (structure data deposition date) |
Authors | Hargrove, T.Y. / Wawrzak, Z. / Guengerich, F.P. / Lepesheva, G.I. |
External links | J. Biol. Chem. / PubMed:32493730 |
Methods | X-ray diffraction |
Resolution | 1.98 Å |
Structure data | PDB-6uez: |
Chemicals | ChemComp-HEM: ChemComp-LAN: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE / monooxygenase / sterol biosynthesis / cytochrome P450 / substrate-induced conformational change |