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TitleRecurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling.
Journal, issue, pagesCell, Vol. 179, Page 1342-1356.e23, Year 2019
Publish dateSep 16, 2019 (structure data deposition date)
AuthorsValencia, A.M. / Collings, C.K. / Dao, H.T. / St Pierre, R. / Cheng, Y.C. / Huang, J. / Sun, Z.Y. / Seo, H.S. / Mashtalir, N. / Comstock, D.E. ...Valencia, A.M. / Collings, C.K. / Dao, H.T. / St Pierre, R. / Cheng, Y.C. / Huang, J. / Sun, Z.Y. / Seo, H.S. / Mashtalir, N. / Comstock, D.E. / Bolonduro, O. / Vangos, N.E. / Yeoh, Z.C. / Dornon, M.K. / Hermawan, C. / Barrett, L. / Dhe-Paganon, S. / Woolf, C.J. / Muir, T.W. / Kadoch, C.
External linksCell / PubMed:31759698
MethodsNMR (solution)
Structure data

PDB-6uch:
SMARCB1 nucleosome-interacting C-terminal alpha helix
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsNUCLEAR PROTEIN / mSWI-SNF complex / BAF complex / Chromatin Remodeling / SMARCB1 / BAF47 / Positive charge cluster / Arginine cluster / Nucleosome Binding / Alpha Helix

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