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TitleMechanistic basis of the inhibition of SLC11/NRAMP-mediated metal ion transport by bis-isothiourea substituted compounds.
Journal, issue, pagesElife, Vol. 8, Year 2019
Publish dateNov 29, 2019 (structure data deposition date)
AuthorsManatschal, C. / Pujol-Gimenez, J. / Poirier, M. / Reymond, J.L. / Hediger, M.A. / Dutzler, R.
External linksElife / PubMed:31804182
MethodsX-ray diffraction
Resolution3.8 Å
Structure data

PDB-6tl2:
Crystal structure of Eremococcus coleocola manganese transporter in complex with an aromatic bis-isothiourea substituted compound
Method: X-RAY DIFFRACTION / Resolution: 3.8 Å

Chemicals

ChemComp-NJZ:
[3-bromanyl-5-(carbamimidoylsulfanylmethyl)phenyl]methyl carbamimidothioate

Source
  • eremococcus coleocola acs-139-v-col8 (bacteria)
KeywordsTRANSPORT PROTEIN / inhibitor complex

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