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-Structure paper
Title | Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis. |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 28, Page 115673-115673, Year 2020 |
Publish date | Nov 22, 2019 (structure data deposition date) |
Authors | Ciccone, L. / Nencetti, S. / Tonali, N. / Fruchart-Gaillard, C. / Shepard, W. / Nuti, E. / Camodeca, C. / Rossello, A. / Orlandini, E. |
External links | Bioorg. Med. Chem. / PubMed:32828431 |
Methods | X-ray diffraction |
Resolution | 1.45 - 1.702 Å |
Structure data | PDB-6ti9: PDB-6tjn: |
Chemicals | ChemComp-ND5: ChemComp-GOL: ChemComp-PGO: ChemComp-HOH: ChemComp-NEK: |
Source |
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Keywords | PROTEIN TRANSPORT / Transthyretin / TTR / inhibitor / complex |