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TitleCrystal Structure of Y55S Serine Hydroxymethyltransferase variant from Streptococcus thermophilus in complex with gem-diamine intermediate of D-serine
Journal, issue, pagesTo Be Published
Publish dateNov 21, 2019 (structure data deposition date)
AuthorsPetrillo, G. / Hernandez, K. / Bujons, J. / Clapes, P. / Uson, I.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.93 Å
Structure data

PDB-6ti4:
SHMT from Streptococcus thermophilus Tyr55Ser variant in complex with PLP/D-Serine/Lys230 gem diamine complex
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-O3Z:
(2~{R})-2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-3-oxidanyl-propanoic acid

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • streptococcus thermophilus (bacteria)
KeywordsTRANSFERASE / Pyridoxal phosphate; X-ray crystallography; hydroxymethyltransferase; proton abstraction; tetrahydrofolate-independent

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