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Structure paper

TitleMAP Kinase-Mediated Activation of RSK1 and MK2 Substrate Kinases.
Journal, issue, pagesStructure, Vol. 28, Page 1101-1113.e5, Year 2020
Publish dateNov 5, 2019 (structure data deposition date)
AuthorsSok, P. / Gogl, G. / Kumar, G.S. / Alexa, A. / Singh, N. / Kirsch, K. / Sebo, A. / Drahos, L. / Gaspari, Z. / Peti, W. / Remenyi, A.
External linksStructure / PubMed:32649858
MethodsX-ray diffraction
Resolution3.7 Å
Structure data

PDB-6tca:
Phosphorylated p38 and MAPKAPK2 complex with inhibitor
Method: X-RAY DIFFRACTION / Resolution: 3.7 Å

Chemicals

ChemComp-39G:
N-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / MAPK / MAPKAPK / phosphorylated / p38 / MK2

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