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Title | Scaffold hopping identifies new triazole-and triazolium-based inhibitors of Leishmania infantum Trypanothione Reductase with potent and selective antileishmanial activity |
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Journal, issue, pages | To Be Published |
Publish date | Oct 26, 2019 (structure data deposition date) |
![]() | Revuelto, A. / de Lucio, H. / Carriles, A. / Garcia Soriano, J.C. / Sanchez-Murcia, P.A. / Hermoso, J.A. / Gago, F. / Camarasa, M.J. / Jimenez-Ruiz, A. / Velazquez, S. |
![]() | Search PubMed |
Methods | X-ray diffraction |
Resolution | 2.8 Å |
Structure data | ![]() PDB-6t97: |
Chemicals | ![]() ChemComp-FAD: ![]() ChemComp-SO4: ![]() ChemComp-GOL: ![]() ChemComp-MWW: ![]() ChemComp-HOH: |
Source |
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![]() | FLAVOPROTEIN / Inhibitor / Complex / Oxidoreductase / Leishmania / Drug |