+Search query
-Structure paper
Title | Identification of 1,2,3-triazolium salt-based inhibitors of Leishmania infantum trypanothione disulfide reductase with enhanced antileishmanial potency in cellulo and increased selectivity. |
---|---|
Journal, issue, pages | Eur. J. Med. Chem., Vol. 244, Page 114878-114878, Year 2022 |
Publish date | Oct 25, 2019 (structure data deposition date) |
![]() | de Lucio, H. / Revuelto, A. / Carriles, A.A. / de Castro, S. / Garcia-Gonzalez, S. / Garcia-Soriano, J.C. / Alcon-Calderon, M. / Sanchez-Murcia, P.A. / Hermoso, J.A. / Gago, F. ...de Lucio, H. / Revuelto, A. / Carriles, A.A. / de Castro, S. / Garcia-Gonzalez, S. / Garcia-Soriano, J.C. / Alcon-Calderon, M. / Sanchez-Murcia, P.A. / Hermoso, J.A. / Gago, F. / Camarasa, M.J. / Jimenez-Ruiz, A. / Velazquez, S. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.5 - 3 Å |
Structure data | ![]() PDB-6t95: ![]() PDB-6t98: |
Chemicals | ![]() ChemComp-FAD: ![]() ChemComp-DMS: ![]() ChemComp-GOL: ![]() ChemComp-SO4: ![]() ChemComp-MWT: ![]() ChemComp-HOH: ![]() ChemComp-MWZ: |
Source |
|
![]() | FLAVOPROTEIN / Inhibitor / Complex / Oxidoreductase / Leishmania / Drug |