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Structure paper

TitleRegulation of RXR-RAR Heterodimers by RXR- and RAR-Specific Ligands and Their Combinations.
Journal, issue, pagesCells, Vol. 8, Year 2019
Publish dateSep 9, 2019 (structure data deposition date)
Authorsle Maire, A. / Teyssier, C. / Balaguer, P. / Bourguet, W. / Germain, P.
External linksCells / PubMed:31694317
MethodsX-ray diffraction
Resolution1.892 - 2.3 Å
Structure data

PDB-6ssq:
Crystal structure of RARbeta LBD in complex with LG 100754
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-6sti:
Crystal structure of RXRalpha LBD in complex with LG 100754 and a coactivator peptide
Method: X-RAY DIFFRACTION / Resolution: 1.892 Å

Chemicals

ChemComp-754:
(2E,4E,6Z)-3-methyl-7-(5,5,8,8-tetramethyl-3-propoxy-5,6,7,8-tetrahydronaphthalen-2-yl)octa-2,4,6-trienoic acid

ChemComp-FLC:
CITRATE ANION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-ACT:
ACETATE ION

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Nuclear receptor / Ligand binding

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