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TitleStructure of the TSC2 GAP Domain: Mechanistic Insight into Catalysis and Pathogenic Mutations.
Journal, issue, pagesStructure, Vol. 28, Page 933-942.e4, Year 2020
Publish dateSep 6, 2019 (structure data deposition date)
AuthorsHansmann, P. / Bruckner, A. / Kiontke, S. / Berkenfeld, B. / Seebohm, G. / Brouillard, P. / Vikkula, M. / Jansen, F.E. / Nellist, M. / Oeckinghaus, A. / Kummel, D.
External linksStructure / PubMed:32502382
MethodsX-ray diffraction
Resolution1.4 Å
Structure data

PDB-6ssh:
Structure of the TSC2 GAP domain
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • chaetomium thermophilum (fungus)
KeywordsSIGNALING PROTEIN / GTPase activating protein

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