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TitleDiscovery of a Series of Potent, Selective and Orally Bioavailable SYK Inhibitors
Journal, issue, pagesTo Be Published
Publish dateSep 6, 2019 (structure data deposition date)
AuthorsRead, J.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.08 Å
Structure data

PDB-6ssb:
syk in complex with compound 30
Method: X-RAY DIFFRACTION / Resolution: 2.08 Å

Chemicals

ChemComp-LUE:
~{N}-[4-[5-[(dimethylamino)methyl]-1-methyl-pyrazol-3-yl]pyrimidin-2-yl]-3-methyl-1-(5-methyl-1,3,4-oxadiazol-2-yl)imidazo[1,5-a]pyridin-7-amine

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / SYK Kinase TRANSFERASE INHIBITOR

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