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Structure paper

TitleFlexible Binding of m6A Reader Protein YTHDC1 to Its Preferred RNA Motif.
Journal, issue, pagesJ Chem Theory Comput, Vol. 15, Page 7004-7014, Year 2019
Publish dateMay 22, 2019 (structure data deposition date)
AuthorsLi, Y. / Bedi, R.K. / Wiedmer, L. / Huang, D. / Sledz, P. / Caflisch, A.
External linksJ Chem Theory Comput / PubMed:31670957
MethodsX-ray diffraction
Resolution1.461 - 2.303 Å
Structure data

PDB-6rt4:
The YTH domain of YTHDC1 protein in complex with m6ACU oligonucleotide
Method: X-RAY DIFFRACTION / Resolution: 1.49 Å

PDB-6rt5:
The YTH domain of YTHDC1 protein in complex with Gm6AC oligonucleotide
Method: X-RAY DIFFRACTION / Resolution: 2.303 Å

PDB-6rt6:
The YTH domain of YTHDC1 protein in complex with GGm6AC oligonucleotide
Method: X-RAY DIFFRACTION / Resolution: 1.461 Å

PDB-6rt7:
The YTH domain of YTHDC1 protein in complex with Gm6ACU oligonucleotide
Method: X-RAY DIFFRACTION / Resolution: 1.73 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / Protein-RNA interaction / epitranscriptomics

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