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TitleCRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJ45031882
Journal, issue, pagesTo Be Published
Publish dateMay 2, 2019 (structure data deposition date)
AuthorsBrown, D.G. / Robinson, C.M. / Pande, V.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.53 Å
Structure data

PDB-6rlq:
CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJ45031882
Method: X-RAY DIFFRACTION / Resolution: 2.53 Å

Chemicals

ChemComp-K8N:
(1~{S},2~{R},3~{S},5~{R})-3-[2-(2-azanyl-3-bromanyl-quinolin-7-yl)ethyl]-5-(4-azanylpyrrolo[2,3-d]pyrimidin-7-yl)cyclop

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSLOCASE / PRMT5 / MEP50 / LIGAND

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