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-Structure paper
Title | Crystal structure ofcis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 116, Page 20644-20654, Year 2019 |
Publish date | Mar 28, 2019 (structure data deposition date) |
Authors | Chen, F. / Lukat, P. / Iqbal, A.A. / Saile, K. / Kaever, V. / van den Heuvel, J. / Blankenfeldt, W. / Bussow, K. / Pessler, F. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:31548418 |
Methods | X-ray diffraction |
Resolution | 1.705 - 2.535 Å |
Structure data | PDB-6r6t: PDB-6r6u: |
Chemicals | ChemComp-HOH: ChemComp-BU3: ChemComp-NA: |
Source |
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Keywords | LYASE / Immunity / Inflammatory response / Innate immunity / Antimicrobial / Decarboxylase / cis-Aconitate / Itaconate |