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Structure paper

TitleReaction with Proteins of a Five-Coordinate Platinum(II) Compound.
Journal, issue, pagesInt J Mol Sci, Vol. 20, Year 2019
Publish dateJan 7, 2019 (structure data deposition date)
AuthorsFerraro, G. / Marzo, T. / Cucciolito, M.E. / Ruffo, F. / Messori, L. / Merlino, A.
External linksInt J Mol Sci / PubMed:30691130
MethodsX-ray diffraction
Resolution1.96 - 2.03 Å
Structure data

PDB-6qe9:
The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and complex I, a pentacoordinate Pt(II) compound containing 2,9-dimethyl-1,10-phenanthroline, dimethylfumarate, methyl and iodine as ligands
Method: X-RAY DIFFRACTION / Resolution: 2.03 Å

PDB-6qea:
The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and complex I, a pentacoordinate Pt(II) compound containing 2,9-dimethyl-1,10-phenanthroline, dimethylfumarate, methyl and iodine as ligands
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-J9H:
pentacoordinate Pt(II) compound

ChemComp-HOH:
WATER

ChemComp-NO3:
NITRATE ION

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

Source
  • bos taurus (domestic cattle)
  • gallus gallus (chicken)
KeywordsHYDROLASE / five-coordinate Pt complexes / anticancer platinum compounds / protein metal coordination / LYASE

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