+Search query
-Structure paper
Title | The Alkyne Moiety as a Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K. |
---|---|
Journal, issue, pages | J. Am. Chem. Soc., Vol. 141, Page 3507-3514, Year 2019 |
Publish date | Dec 21, 2018 (structure data deposition date) |
Authors | Mons, E. / Jansen, I.D.C. / Loboda, J. / van Doodewaerd, B.R. / Hermans, J. / Verdoes, M. / van Boeckel, C.A.A. / van Veelen, P.A. / Turk, B. / Turk, D. / Ovaa, H. |
External links | J. Am. Chem. Soc. / PubMed:30689386 |
Methods | X-ray diffraction |
Resolution | 1.7 Å |
Structure data | PDB-6qbs: |
Chemicals | ChemComp-HVW: ChemComp-CA: ChemComp-CL: ChemComp-HOH: |
Source |
|
Keywords | HYDROLASE / Covalent Inhibitor / Cathepsin K |