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Title | Glucopyranosylidene-spiro-imidazolinones, a New Ring System: Synthesis and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetics and X-ray Crystallography. |
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Journal, issue, pages | J. Med. Chem., Vol. 62, Page 6116-6136, Year 2019 |
Publish date | Dec 18, 2018 (structure data deposition date) |
![]() | Szabo, K.E. / Kyriakis, E. / Psarra, A.G. / Karra, A.G. / Sipos, A. / Docsa, T. / Stravodimos, G.A. / Katsidou, E. / Skamnaki, V.T. / Liggri, P.G.V. ...Szabo, K.E. / Kyriakis, E. / Psarra, A.G. / Karra, A.G. / Sipos, A. / Docsa, T. / Stravodimos, G.A. / Katsidou, E. / Skamnaki, V.T. / Liggri, P.G.V. / Zographos, S.E. / Mandi, A. / Kiraly, S.B. / Kurtan, T. / Leonidas, D.D. / Somsak, L. |
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Methods | X-ray diffraction |
Resolution | 2.35 - 2.4 Å |
Structure data | ![]() PDB-6qa6: ![]() PDB-6qa7: ![]() PDB-6qa8: |
Chemicals | ![]() ChemComp-DMS: ![]() ChemComp-HT8: ![]() ChemComp-PLP: ![]() ChemComp-HOH: ![]() ChemComp-HTW: ![]() ChemComp-HTE: |
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