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Structure paper

TitleLigand-dependent downregulation of MR1 cell surface expression.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 117, Page 10465-10475, Year 2020
Publish dateJul 20, 2019 (structure data deposition date)
AuthorsSalio, M. / Awad, W. / Veerapen, N. / Gonzalez-Lopez, C. / Kulicke, C. / Waithe, D. / Martens, A.W.J. / Lewinsohn, D.M. / Hobrath, J.V. / Cox, L.R. ...Salio, M. / Awad, W. / Veerapen, N. / Gonzalez-Lopez, C. / Kulicke, C. / Waithe, D. / Martens, A.W.J. / Lewinsohn, D.M. / Hobrath, J.V. / Cox, L.R. / Rossjohn, J. / Besra, G.S. / Cerundolo, V.
External linksProc. Natl. Acad. Sci. USA / PubMed:32341160
MethodsX-ray diffraction
Resolution1.96 - 2.14 Å
Structure data

PDB-6pvc:
Structure of human MAIT A-F7 TCR in complex with human MR1-DB28
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

PDB-6pvd:
Structure of human MAIT A-F7 TCR in complex with human MR1-NV18.1
Method: X-RAY DIFFRACTION / Resolution: 2.14 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-P1J:
N-(2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbonyl)-beta-alanine

ChemComp-NA:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-N18:
methyl N-(2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbonyl)-beta-alaninate

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / MAIT / MR1

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