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-Structure paper
Title | Targetable HER3 functions driving tumorigenic signaling in HER2-amplified cancers. |
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Journal, issue, pages | Cell Rep, Vol. 38, Page 110291-110291, Year 2022 |
Publish date | Apr 24, 2019 (structure data deposition date) |
![]() | Campbell, M.R. / Ruiz-Saenz, A. / Peterson, E. / Agnew, C. / Ayaz, P. / Garfinkle, S. / Littlefield, P. / Steri, V. / Oeffinger, J. / Sampang, M. ...Campbell, M.R. / Ruiz-Saenz, A. / Peterson, E. / Agnew, C. / Ayaz, P. / Garfinkle, S. / Littlefield, P. / Steri, V. / Oeffinger, J. / Sampang, M. / Shan, Y. / Shaw, D.E. / Jura, N. / Moasser, M.M. |
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Methods | X-ray diffraction |
Resolution | 2.501 Å |
Structure data | ![]() PDB-6op9: |
Chemicals | ![]() ChemComp-DB8: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE/TRANSFERASE inhibitor / RECEPTOR TYROSINE KINASE / PSEUDOKINASE / BOSUTINIB / MEMBRANE / SIGNALING PROTEIN / TRANSFERASE-TRANSFERASE inhibitor complex |