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-Structure paper
Title | Molecular Determinants of Epistasis in HIV-1 Protease: Elucidating the Interdependence of L89V and L90M Mutations in Resistance. |
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Journal, issue, pages | Biochemistry, Vol. 58, Page 3711-3726, Year 2019 |
Publish date | Apr 23, 2019 (structure data deposition date) |
![]() | Henes, M. / Kosovrasti, K. / Lockbaum, G.J. / Leidner, F. / Nachum, G.S. / Nalivaika, E.A. / Bolon, D.N.A. / Kurt Yilmaz, N. / Schiffer, C.A. / Whitfield, T.W. |
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Methods | X-ray diffraction |
Resolution | 1.822 - 2.127 Å |
Structure data | ![]() PDB-6oos: ![]() PDB-6oot: ![]() PDB-6oou: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-017: ![]() ChemComp-HOH: |
Source |
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![]() | hydrolase/hydrolase inhibitor / HIV / NL4-3 PROTEASE / DRUG RESISTANCE / PROTEASE INHIBITOR / HYDROLASE INHIBITOR COMPLEX / HYDROLASE / hydrolase-hydrolase inhibitor complex |