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Structure paper

TitleMolecular basis for the binding and selective dephosphorylation of Na+/H+exchanger 1 by calcineurin.
Journal, issue, pagesNat Commun, Vol. 10, Page 3489-3489, Year 2019
Publish dateJan 31, 2019 (structure data deposition date)
AuthorsHendus-Altenburger, R. / Wang, X. / Sjogaard-Frich, L.M. / Pedraz-Cuesta, E. / Sheftic, S.R. / Bendsoe, A.H. / Page, R. / Kragelund, B.B. / Pedersen, S.F. / Peti, W.
External linksNat Commun / PubMed:31375679
MethodsX-ray diffraction
Resolution1.9 - 2.3 Å
Structure data

PDB-6nuc:
Structure of Calcineurin in complex with NHE1 peptide
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-6nuf:
Structure of Calcineurin in complex with NHE1 peptide
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-6nuu:
Structure of Calcineurin mutant in complex with NHE1 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-FE:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-NA:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-PGE:
TRIETHYLENE GLYCOL

Source
  • homo sapiens (human)
KeywordsHYDROLASE/Calcium Binding Protein / Ser/thr phosphatase / complex / HYDROLASE / HYDROLASE-Calcium Binding Protein complex

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