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Structure paper

TitleStructural insight into YcbB-mediated beta-lactam resistance in Escherichia coli.
Journal, issue, pagesNat Commun, Vol. 10, Page 1849-1849, Year 2019
Publish dateJan 30, 2019 (structure data deposition date)
AuthorsCaveney, N.A. / Caballero, G. / Voedts, H. / Niciforovic, A. / Worrall, L.J. / Vuckovic, M. / Fonvielle, M. / Hugonnet, J.E. / Arthur, M. / Strynadka, N.C.J.
External linksNat Commun / PubMed:31015395
MethodsX-ray diffraction
Resolution2.2 - 2.76 Å
Structure data

PDB-6ntw:
Crystal structure of E. coli YcbB
Method: X-RAY DIFFRACTION / Resolution: 2.76 Å

PDB-6ntz:
Crystal structure of E. coli PBP5-meropenem
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-MXR:
(2S,3R,4S)-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • escherichia coli (strain k12) (bacteria)
  • escherichia coli (E. coli)
Keywordstransferase/transferase inhibitor / l / d-transpeptidase / TRANSFERASE / transferase-transferase inhibitor complex / hydrolase/antibiotic / carboxypeptidase / HYDROLASE / hydrolase-hydrolase inhibitor complex / hydrolase-antibiotic complex

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