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-Structure paper
Title | Deciphering the Allosteric Binding Mechanism of the Human Tropomyosin Receptor Kinase A ( hTrkA) Inhibitors. |
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Journal, issue, pages | Acs Chem. Biol., Vol. 14, Page 1205-1216, Year 2019 |
Publish date | Jan 18, 2019 (structure data deposition date) |
![]() | Subramanian, G. / Johnson, P.D. / Zachary, T. / Roush, N. / Zhu, Y. / Bowen, S.J. / Janssen, A. / Duclos, B.A. / Williams, T. / Javens, C. ...Subramanian, G. / Johnson, P.D. / Zachary, T. / Roush, N. / Zhu, Y. / Bowen, S.J. / Janssen, A. / Duclos, B.A. / Williams, T. / Javens, C. / Shalaly, N.D. / Molina, D.M. / Wittwer, A.J. / Hirsch, J.L. |
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Methods | X-ray diffraction |
Resolution | 1.97 - 2.31 Å |
Structure data | ![]() PDB-6npt: ![]() PDB-6nsp: ![]() PDB-6nss: |
Chemicals | ![]() ChemComp-KWY: ![]() ChemComp-HOH: ![]() ChemComp-L0P: ![]() ChemComp-L0M: |
Source |
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![]() | TRANSFERASE / TRK-A KINASE DOMAIN HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR Inhibitor / TRANSFERASE/TRANSFERASE Inhibitor / TRANSFERASE-TRANSFERASE Inhibitor complex / TRK-A KINASE DOMAIN / HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR / Inhibitor |