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TitleCrystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with 2'-deoxycytidine and B9D
Journal, issue, pagesTo Be Published
Publish dateJan 14, 2019 (structure data deposition date)
AuthorsThompson, A.P. / Polyak, S.W. / Wegener, K.L. / Bruning, J.B.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.343 Å
Structure data

PDB-6nn0:
Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with 2'-deoxycytidine and fragment degradation product B9D
Method: X-RAY DIFFRACTION / Resolution: 2.343 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-KSJ:
[(1S,2R)-2-(2-hydroxybenzene-1-carbonyl)cyclopentyl]acetic acid

ChemComp-KSP:
[(1R,2S)-2-(2-hydroxybenzene-1-carbonyl)cyclopentyl]acetic acid

ChemComp-CTN:
4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (strain atcc 25618 / h37rv) (bacteria)
KeywordsTRANSFERASE / enzyme / synthetase / nucleotide triphosphate binding

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