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Structure paper

TitleAntibody domain exchange is an immunological solution to carbohydrate cluster recognition.
Journal, issue, pagesScience, Vol. 300, Page 2065-2071, Year 2003
Publish dateNov 14, 2018 (structure data deposition date)
AuthorsCalarese, D.A. / Scanlan, C.N. / Zwick, M.B. / Deechongkit, S. / Mimura, Y. / Kunert, R. / Zhu, P. / Wormald, M.R. / Stanfield, R.L. / Roux, K.H. ...Calarese, D.A. / Scanlan, C.N. / Zwick, M.B. / Deechongkit, S. / Mimura, Y. / Kunert, R. / Zhu, P. / Wormald, M.R. / Stanfield, R.L. / Roux, K.H. / Kelly, J.W. / Rudd, P.M. / Dwek, R.A. / Katinger, H. / Burton, D.R. / Wilson, I.A.
External linksScience / PubMed:12829775
MethodsX-ray diffraction
Resolution1.747 - 3 Å
Structure data

PDB-6n2x:
Anti-HIV-1 Fab 2G12 + Man9 re-refinement
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-6n32:
Anti-HIV-1 Fab 2G12 re-refinement
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-6n35:
Anti-HIV-1 Fab 2G12 + Man1-2 re-refinement
Method: X-RAY DIFFRACTION / Resolution: 1.747 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-BEZ:
BENZOIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-MAN:
alpha-D-mannopyranose

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / antibody / carbohydrate / HIV-1

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