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TitleCisplatin protects mice from challenge ofCryptococcus neoformansby targeting the Prp8 intein.
Journal, issue, pagesEmerg Microbes Infect, Vol. 8, Page 895-908, Year 2019
Publish dateOct 30, 2018 (structure data deposition date)
AuthorsLi, Z. / Fu, B. / Green, C.M. / Liu, B. / Zhang, J. / Lang, Y. / Chaturvedi, S. / Belfort, M. / Liao, G. / Li, H.
External linksEmerg Microbes Infect / PubMed:31223062
MethodsX-ray diffraction
Resolution2.594 - 3.06 Å
Structure data

PDB-6mwy:
The Prp8 intein of Cryptococcus gattii
Method: X-RAY DIFFRACTION / Resolution: 2.594 Å

PDB-6myl:
The Prp8 intein-cisplatin complex
Method: X-RAY DIFFRACTION / Resolution: 3.06 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-PT:
Unknown entry

Source
  • cryptococcus gattii serotype b (fungus)
KeywordsHYDROLASE / Intein / Fungus / Cryptococcus gattii / hydrolase/hydrolase inhibitor / Prp8 / cisplatin / hydrolase-hydrolase inhibitor complex

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