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TitleDistinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors.
Journal, issue, pagesNat Commun, Vol. 10, Page 5242-5242, Year 2019
Publish dateOct 12, 2018 (structure data deposition date)
AuthorsAlmeida, C.F. / Sundararaj, S. / Le Nours, J. / Praveena, T. / Cao, B. / Burugupalli, S. / Smith, D.G.M. / Patel, O. / Brigl, M. / Pellicci, D.G. ...Almeida, C.F. / Sundararaj, S. / Le Nours, J. / Praveena, T. / Cao, B. / Burugupalli, S. / Smith, D.G.M. / Patel, O. / Brigl, M. / Pellicci, D.G. / Williams, S.J. / Uldrich, A.P. / Godfrey, D.I. / Rossjohn, J.
External linksNat Commun / PubMed:31748533
MethodsX-ray diffraction
Resolution1.7 - 3 Å
Structure data

PDB-6mra:
Diversity in the type II Natural Killer T cell receptor repertoire and antigen specificity leads to differing CD1d docking strategies
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-6mss:
Diversity in the type II Natural Killer T cell receptor repertoire and antigen specificity leads to differing CD1d docking strategies
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-SRV:
(2S)-2-(heptadecanoyloxy)-3-{[(10S)-10-methyloctadecanoyl]oxy}propyl alpha-D-glucopyranosiduronic acid

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / NKT cells / CD1d molecule / microbial lipid antigen

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