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| Title | Exploring substituent diversity on pyrrolidine-aryltriazole iminosugars: Structural basis of beta-glucocerebrosidase inhibition. |
|---|---|
| Journal, issue, pages | Bioorg. Chem., Vol. 86, Page 652-664, Year 2019 |
| Publish date | Oct 5, 2018 (structure data deposition date) |
Authors | Martinez-Bailen, M. / Carmona, A.T. / Patterson-Orazem, A.C. / Lieberman, R.L. / Ide, D. / Kubo, M. / Kato, A. / Robina, I. / Moreno-Vargas, A.J. |
External links | Bioorg. Chem. / PubMed:30825709 |
| Methods | X-ray diffraction |
| Resolution | 2.1 Å |
| Structure data | ![]() PDB-6moz: |
| Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-NA: ![]() ChemComp-JXA: ![]() ChemComp-PO4: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
| Source |
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Keywords | HYDROLASE / TIM-BARREL / GLYCOSIDASE / CEREZYME / HYDROLYSIS / INHIBITOR COMPLEX / PHARMACOLOGICAL CHAPERONE |
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