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TitleRepurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis.
Journal, issue, pagesStructure, Vol. 28, Page 63-74.e4, Year 2020
Publish dateSep 10, 2018 (structure data deposition date)
AuthorsSkiba, M.A. / Tran, C.L. / Dan, Q. / Sikkema, A.P. / Klaver, Z. / Gerwick, W.H. / Sherman, D.H. / Smith, J.L.
External linksStructure / PubMed:31785925
MethodsX-ray diffraction
Resolution2.589 - 2.794 Å
Structure data

PDB-6mfc:
GphF GNAT-like decarboxylase
Method: X-RAY DIFFRACTION / Resolution: 2.589 Å

PDB-6mfd:
GphF GNAT-like decarboxylase in complex with isobutyryl-CoA
Method: X-RAY DIFFRACTION / Resolution: 2.794 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-CO6:
ISOBUTYRYL-COENZYME A / antibiotic*YM

ChemComp-ACT:
ACETATE ION

Source
  • cystobacter violaceus (bacteria)
KeywordsLYASE / decarboxylase

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