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Structure paper

TitleJMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes.
Journal, issue, pagesElife, Vol. 9, Year 2020
Publish dateSep 7, 2018 (structure data deposition date)
AuthorsLee, S. / Liu, H. / Hill, R. / Chen, C. / Hong, X. / Crawford, F. / Kingsley, M. / Zhang, Q. / Liu, X. / Chen, Z. ...Lee, S. / Liu, H. / Hill, R. / Chen, C. / Hong, X. / Crawford, F. / Kingsley, M. / Zhang, Q. / Liu, X. / Chen, Z. / Lengeling, A. / Bernt, K.M. / Marrack, P. / Kappler, J. / Zhou, Q. / Li, C.Y. / Xue, Y. / Hansen, K. / Zhang, G.
External linksElife / PubMed:32048991
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-6mev:
Structure of JMJD6 bound to Mono-Methyl Arginine.
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-AKG:
2-OXOGLUTARIC ACID

ChemComp-FE:
Unknown entry

ChemComp-NMM:
(2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid / inhibitor*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Jumonji / Arginine / Methyl / endopeptidase / exopeptidase

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