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Structure paper

TitleStructure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode.
Journal, issue, pagesNat Commun, Vol. 11, Page 4160-4160, Year 2020
Publish dateAug 8, 2019 (structure data deposition date)
AuthorsShiimura, Y. / Horita, S. / Hamamoto, A. / Asada, H. / Hirata, K. / Tanaka, M. / Mori, K. / Uemura, T. / Kobayashi, T. / Iwata, S. / Kojima, M.
External linksNat Commun / PubMed:32814772
MethodsX-ray diffraction
Resolution1.753 - 3.3 Å
Structure data

PDB-6ko5:
Complex structure of Ghrelin receptor with Fab
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

PDB-6ks2:
Structure of anti-Ghrelin receptor antibody
Method: X-RAY DIFFRACTION / Resolution: 1.753 Å

Chemicals

ChemComp-8QX:
6-(4-bromanyl-2-fluoranyl-phenoxy)-2-methyl-3-[[(3~{S})-1-propan-2-ylpiperidin-3-yl]methyl]pyrido[3,2-d]pyrimidin-4-one

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsMEMBRANE PROTEIN / G-PROTEIN COUPLED RECEPTOR / GHRELIN / ANTAGONIST-BOUND COMPLEX / IMMUNE SYSTEM / antibody

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