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TitleCrystal structure of BRD4 Bromodomain1 with an inhibitor
Journal, issue, pagesTo be published
Publish dateJul 4, 2019 (structure data deposition date)
AuthorsXiao, S. / Li, Z. / Chen, S. / Zhou, B. / Luo, C.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.12154661767 Å
Structure data

PDB-6kee:
Crystal structure of BRD4 Bromodomain1 with an inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.12154661767 Å

Chemicals

ChemComp-D7U:
6-[2-[2,4-bis(fluoranyl)phenoxy]-5-(methylsulfonylmethyl)pyridin-3-yl]-8-methyl-2H-pyrrolo[1,2-a]pyrazin-1-one

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Antitumor / BET proteins / Bromodomain inhibitor / Epigenetic readers / ANTITUMOR PROTEIN

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