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-Structure paper
Title | Synthesis, SAR study, and biological evaluation of novel 2,3-dihydro-1H-imidazo[1,2-a]benzimidazole derivatives as phosphodiesterase 10A inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 27, Page 3692-3706, Year 2019 |
Publish date | Jul 3, 2019 (structure data deposition date) |
Authors | Chino, A. / Honda, S. / Morita, M. / Yonezawa, K. / Hamaguchi, W. / Amano, Y. / Moriguchi, H. / Yamazaki, M. / Aota, M. / Tomishima, M. / Masuda, N. |
External links | Bioorg. Med. Chem. / PubMed:31301949 |
Methods | X-ray diffraction |
Resolution | 2.44 - 3.1 Å |
Structure data | PDB-6kdx: PDB-6kdz: PDB-6ke0: |
Chemicals | ChemComp-ZN: ChemComp-MG: ChemComp-D6X: ChemComp-HOH: ChemComp-D79: ChemComp-D7C: |
Source |
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Keywords | HYDROLASE / Inhibitor |