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-Structure paper
Title | Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins. |
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Journal, issue, pages | Eur. J. Med. Chem., Vol. 182, Page 111633-111633, Year 2019 |
Publish date | May 5, 2019 (structure data deposition date) |
Authors | Chen, D. / Lu, T. / Yan, Z. / Lu, W. / Zhou, F. / Lyu, X. / Xu, B. / Jiang, H. / Chen, K. / Luo, C. / Zhao, Y. |
External links | Eur. J. Med. Chem. / PubMed:31461688 |
Methods | X-ray diffraction |
Resolution | 1.251 - 1.935 Å |
Structure data | PDB-6k04: PDB-6k05: |
Chemicals | ChemComp-CQF: ChemComp-HOH: ChemComp-MES: |
Source |
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Keywords | ANTITUMOR PROTEIN / Antitumor; BET proteins; Bromodomain inhibitor; Epigenetic readers |