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TitleIdentify liver X receptor beta modulator building blocks by developing a fluorescence polarization-based competition assay.
Journal, issue, pagesEur. J. Med. Chem., Vol. 178, Page 458-467, Year 2019
Publish dateFeb 22, 2019 (structure data deposition date)
AuthorsZhang, Z. / Chen, H. / Chen, Z. / Ding, P. / Ju, Y. / Gu, Q. / Xu, J. / Zhou, H.
External linksEur. J. Med. Chem. / PubMed:31202993
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-6jio:
Human LXR-beta in complex with a ligand
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-BQ3:
tert-butyl 7-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN / Nuclear receptor

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