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TitleCyclic Peptidic Mimetics of Apollo Peptides Targeting Telomeric Repeat Binding Factor 2 (TRF2) and Apollo Interaction.
Journal, issue, pagesACS Med Chem Lett, Vol. 9, Page 507-511, Year 2018
Publish dateJan 14, 2019 (structure data deposition date)
AuthorsChen, X. / Liu, L. / Chen, Y. / Yang, Y. / Yang, C.Y. / Guo, T. / Lei, M. / Sun, H. / Wang, S.
External linksACS Med Chem Lett / PubMed:29795768
MethodsX-ray diffraction
Resolution2.05 Å
Structure data

PDB-6j67:
Crystal structure of the compound 34 in a complex with TRF2
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN / Telomere proteins / shelterin complex / TRF2 / Apollo / inhibitor

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