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TitleX-ray Structure Analysis of Human Oxidized Nucleotide Hydrolase MTH1 using Crystals Obtained under Microgravity.
Journal, issue, pagesInt. J. Microgravity Sci. Appl., Vol. 36, Year 2019
Publish dateOct 12, 2018 (structure data deposition date)
AuthorsNakamura, T. / Hirata, K. / Fujimiya, K. / Chirifu, M. / Arimori, T. / Tamada, T. / Ikemizu, S. / Yamagata, Y.
External linksInt. J. Microgravity Sci. Appl. / Search PubMed
MethodsX-ray diffraction
Resolution1.04 Å
Structure data

PDB-6ijy:
Crystal structure of human MTH1(G2K/C87A/C104S mutant) in complex with 8-oxo-dGTP determined using a crystal obtained under microgravity
Method: X-RAY DIFFRACTION / Resolution: 1.04 Å

Chemicals

ChemComp-8DG:
8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

ChemComp-NA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / ALPHA-BETA-ALPHA SANDWICH / DNA DAMAGE / DNA REPAIR / DNA REPLICATION

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